The relationship between periodontal disease and hypertension

1. A researcher is looking at the relationship between periodontal disease and hypertension in a population of men and women. He/she decides to collect relevant information on the following variables as potential confounders in the investigation: gender (M/F), education status (<High School, High School, >High School), annual income ($), health status (dissatisfied, somewhat dissatisfied, somewhat satisfied, satisfied), Body Mass Index (weight kg/height m2). Describe each of the relevant co-variables as ordinal, categorical, or quantitative






2. Suppose a researcher conducts an analysis of the relationship between cardiovascular disease and type II diabetes. The basic summary of the findings are presented in the following table.


Patient BMI (kg/m2) Hypertension (Y/N) Diabetes Type II (Y/N) Smoking status (Never, Quit, Social, Current) Education Status (<High, High, >High) Alcohol (>2 drinks a day? Y/N) Religious Background (Catholic, Jewish, Muslim, Other) Ethnicity (AA, W, A, H, Other)
A 27 N N Current <High Y Catholic AA
B 34 Y Y Never >High Y Other A
C 21 N N Quit High Y Other W
D 28 Y N Social >High N Muslim W
E 36 Y Y Current <High Y Jewish W



A) Describe the following in reference to their status as a variable, observation, or value: column 3, row 5, column 3/row 2, column 9.

B) Are any of the variables included in the study ordinal? If so, identify the ordinal variables.


3. Suppose a researcher conducts an experiment to assess the measuring capabilities of a new device aimed at detecting the boiling point of a chemical. The chemical has a known boiling point of 120 degrees Fahrenheit. His measurement device is tested 10 times, and results in the following measurements for boiling point. What can we say about the device with regards to its precision, accuracy, and potential bias?


Measurement Boiling Point (degrees Fahrenheit)
1 129
2 137
3 136
4 141
5 139
6 142
7 136
8 127
9 143
10 123












4. Suppose a researcher is investigating the measurement ability of a new device intended to read the freezing point of a chemical compound. The substance used in the investigation has a known freezing point of -24 degrees Celsius. The researcher conducted a series of 10 sample measurements of the freezing point, and the results are represented below. What can we say about the device with regards to its precision, and potential bias?


Measurement Freezing Point (degrees Celsius)
1 -26
2 -18
3 -32
4 -31
5 -24
6 -24
7 -24
8 -24
9 -11
10 -37




5. A researcher is investigating a new screening tool that is intended to help prevent the onset of breast cancer in young women. Suppose he tests the new device on a group of 10 women. The following table shows the test result and true breast cancer status of each of the women. What can we say about the new device with regards to its accuracy?


Patient Test Result True Cancer Status
A + +
B + +
C +
D +
E +
F +
G +
H +
J +











6. A surveyor decides to sample students randomly from a classroom in to get information about teacher satisfaction. There are 29 students in the class, and the surveyor has randomly assigned each of the students a number. The surveyor wishes to randomly select 10 students using the following number table.


741928 657381 104823 571628 021598 204878 123596 897635 234807 646079 659735


A) What kind of sample is this?

B) What assumptions must be made about the population in to continue with the sampling design?

C) Assuming the above assumptions do hold, what are the numbers corresponding to the 10 students in the sample that would be selected from the classroom?









7. A surveyor is determined to sample homeowners in south Philadelphia before the next local election in to assess key issues that people want to see changes for this year. Suppose the surveyor decides that he will first collect a list of eligible voters from the county, and separate that list into four groups based on annual income. Then, the surveyor randomly assigns each household a number 01-10 within each group of income. The surveyor will select 4 households from each income group using the following random number table. Once 4 households are selected for one group, the surveyor would continue with the next on the same line of the table.


081203 071072 058436 080695 010354 080951 213607 041573 083947 101503 785409


A) What kind of sampling strategy is this?

B) Which households would be selected for each income group from this table?










8. A surveyor wants to sample a city for the local Public Health Office in to assess asthma rates annually. In to get the best estimate for the project, the surveyor first decides to sample 2 of 15 census tracts, and then to sample 5 households from each tract. Assume there are only 10 households in each tract. The surveyor randomly assigns each tract in the city a number 01-15, and each household in each tract a number 01-10. Use the following random number table to select each tract, and then each household, continuing along the line.


058791 211403 098746 170528 086401 370614 097810 036418 340514


A) What kind of sampling strategy is this?

B) Which census tracts and households will be selected?














9. A surveyor decides to sample a number of households in a community for a needs assessment project. Suppose he does a sample size calculation and determines that he only needs to sample 15 out of 100 households. What is the sampling fraction?







10. Investigators are interested in the relationship between sleep apnea and Alzheimer’s disease. In to more thoroughly understand the relationship, these investigators decide to recruit 50 participants with Alzheimer’s and 50 participants without Alzheimer’s, and look at their history of sleep apnea.


A) What type of study design is this?

B) What are the explanatory and response variables?





The following measurements represent the systolic and diastolic blood pressures (mm HG) for a group of individuals awaiting confirmation for enrollment in a study investigating the efficacy of a new anti-hypertensive medication.


118 73
132 81
147 87
145 91
129 73
126 81
132 83
156 97
164 102
162 101
167 103
121 78


A) Create a stem-and-leaf plot for both systolic and diastolic blood pressure.

B) Suppose that Hypertension is categorized by a Systolic blood pressure above 159 mm HG or a diastolic blood pressure above 99 mm HG. What is the relative frequency of the potential participants with hypertension?




The following table reports the fasting glucose levels of a sample of potential participants in a research study investigating the efficacy of a new insulin-type drug.


Patient Fasting Glucose (mg/dL) Patient Fasting Glucose (mg/dL)
A 117 A 112
B 125 B 132
C 129 C 118
D 116 D 119
E 134 E 134
F 108 F 126
G 127 G 124



A) Calculate the mean, median, mode, and standard deviation for the group.

B) Are there any potential outliers that may be affecting the statistics calculated in part A?

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